Premature ovarian failure is a disorder that can be seen in women before the age of 40. These people may not experience menstruation at all, or if they did experience menstruation, their menstruation stopped before the age of 40. It should be kept in mind that not all women who stop menstruating before the age of 40 have premature menopause, and this diagnosis must be confirmed with hormonal tests.
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Symptoms of premature ovarian failure include:
- weight gain
- Hirsutism
- acne
- Acanthosis nigricans
What is the cause of premature ovarian failure?
In many cases, there may be a genetic cause for the premature cessation of ovarian function, which causes the loss of eggs by disrupting ovarian function. In some cases, there may be an immune disorder that leads to an abnormal response of the body to its own tissues. Sometimes inflammation in the ovary due to some infections such as mumps causes premature menopause. Also, in some cases, chemotherapy or radiation therapy causes premature menopause. Surgeries that lead to the removal of the ovaries, causing great damage to the ovaries, or laparoscopies that are performed along with “cauterization” of the ovaries, i.e. burning the ovaries, can also be other causes of premature menopause or premature ovarian failure but it should be noted that in 90% of cases, the causes of premature ovarian failure remain unknown.
Complications of premature ovarian failure
- Infertility: the inability to conceive can be considered one of the most important complications of premature ovarian failure, although there is a possibility of pregnancy.
- Heart diseases: early loss of estrogen caused by premature ovarian failure can increase the risk of heart diseases.
- Osteoporosis: estrogen helps in the proper balance of bones. Women with premature ovarian failure have lower estrogen levels. Thus, they are at risk of bone damage and osteoporosis.
- Anxiety and depression: the possibility of infertility and other complications caused by premature ovarian failure can lead to anxiety and depression.
- Dementia: a decrease in the amount of estrogen caused by premature ovarian failure can lead to the possibility of dementia in some people.
Diagnosis of premature ovarian failure
Diagnosis of premature ovarian failure includes physical examination and review of the patient’s records. Some tests that are used to diagnose premature ovarian failure include:
- pregnancy test
- Follicle stimulating hormone test
- Estradiol test
- Prolactin test
- karyotype
Treatment of premature ovarian failure
In these people, since the possibility of heart diseases increases greatly due to the decrease of female hormones, hormone treatments should be started as soon as possible and remind her that the side effects of hormone treatment in her, who is younger than normal menopausal people, is negligible and on the other hand, the use of these drugs can lead to a normal life for them. In these people, together with the relevant controls, estrogen tablets with progesterone are given, and sometimes this treatment leads to small monthly bleedings, but one should not be mistaken and think that with this work, the function of the ovaries has returned; Of course, in a small number of cases (about 5-10%), the ovary returns to normal activity for a short period of time and the possibility of fertility also arises. In most of these people, it is not possible to get pregnant naturally, but they can use a donated egg for fertilization. Patients with premature ovarian failure should walk for half an hour every day or do sports that make bones strong, use calcium-containing materials such as dairy products and enough vegetables in their diet. Taking calcium D drug and estrogen and progesterone drugs are recommended to prevent osteoporosis under the supervision of a doctor.
Adib Elixir, a producer of products such as Inolix urine burn ointment, Fengrix capsule (diabetes medicine), Daminest capsule (women’s sexual enhancement), Vigress capsule (men’s sexual enhancement), Silidianin fatty liver treatment capsule, Punica capsule (ovarian cyst medicine), Karodib tea, Adib Derm burn ointment (ointment for burns), Adib Derm’s acne cream and anti-stain cream, Estorest capsule (treatment of menopause problems), scar healing ointment (ointment for scars) etc. are available in Iran.